Lisa Merck

Lisa Merck, MD, MPH, MA, FACEP

Associate Professor | Emergency Medicine; Affiliate Associate Professor | Division Of Neurocritical Care, Department Of Neurology; Affiliate Associate Professor | Health Outcomes And Biomedical Informatics; Director, Clinical Trials Collaborative

Department: Department of Emergency Medicine
Business Phone: (352) 265-5911

About Lisa Merck

Dr. Lisa H. Merck is Associate Professor & Vice Chair of Research in the Department of Emergency Medicine at the University of Florida. Dr. Merck holds appointments as an Affiliate Associate Professor in the Department of Neurology, Division of Neurocritical Care and the Department of Health Outcomes and Biomedical Informatics at the University of Florida, Gainesville.

Research Profile

Dr. Merck’s research focuses on neurological emergencies, critical care, resuscitation, and the COVID pandemic response. Dr Merck works with undergraduate, graduate, and post doctoral students to facilitate education in clinical research. Dr. Merck facilitates local, national, and international clinical trial implementation.

Publications

2021
Computer-Assisted Measurement of Traumatic Brain Hemorrhage Volume Is More Predictive of Functional Outcome and Mortality than Standard ABC/2 Method: An Analysis of Computed Tomography Imaging Data from the Progesterone for Traumatic Brain Injury Experimental Clinical Treatment Phase-III Trial.
Journal of neurotrauma. 38(5):604-615 [DOI] 10.1089/neu.2020.7209. [PMID] 33191851.
2020
A Comparative Study of 2D Image Segmentation Algorithms for Traumatic Brain Lesions Using CT Data from the ProTECTIII Multicenter Clinical Trial
Medical Imaging 2020: Imaging Informatics for Healthcare, Research, and Applications. [DOI] 10.1117/12.2566332.
2020
Diagnostic Accuracy of Non-Invasive Thermal Evaluation of Ventriculoperitoneal Shunt Flow in Shunt Malfunction: A Prospective, Multi-Site, Operator-Blinded Study.
Neurosurgery. 87(5):939-948 [DOI] 10.1093/neuros/nyaa128. [PMID] 32459841.
2020
Proceedings from the Neurotherapeutics Symposium on Neurological Emergencies: Shaping the Future of Neurocritical Care.
Neurocritical care. 33(3):636-645 [DOI] 10.1007/s12028-020-01085-0. [PMID] 32959201.
2019
Association of Very Early Serum Levels of S100B, Glial Fibrillary Acidic Protein, Ubiquitin C-Terminal Hydrolase-L1, and Spectrin Breakdown Product with Outcome in ProTECT III.
Journal of neurotrauma. 36(20):2863-2871 [DOI] 10.1089/neu.2018.5809. [PMID] 30794101.
2019
Efficacy of Computed Tomography Utilization in the Assessment of Acute Traumatic Brain Injury in Adult and Pediatric Emergency Department Patients.
Rhode Island medical journal (2013). 102(9):33-35 [PMID] 31675785.
View on: PubMed
2019
The Effect of Goal-Directed Therapy on Patient Morbidity and Mortality After Traumatic Brain Injury: Results From the Progesterone for the Treatment of Traumatic Brain Injury III Clinical Trial.
Critical care medicine. 47(5):623-631 [DOI] 10.1097/CCM.0000000000003680. [PMID] 30730438.
2018
Comparative Analysis of Emergency Medical Service Provider Workload During Simulated Out-of-Hospital Cardiac Arrest Resuscitation Using Standard Versus Experimental Protocols and Equipment.
Simulation in healthcare : journal of the Society for Simulation in Healthcare. 13(6):376-386 [DOI] 10.1097/SIH.0000000000000339. [PMID] 30407958.
2018
Is There a Neurologist in the House? A Summary of the Current State of Neurovascular Rotations for Emergency Medicine Residents.
AEM education and training. 2(Suppl Suppl 1):S56-S67 [DOI] 10.1002/aet2.10200. [PMID] 30607380.
2018
Reply to: Prehospital Intubation: Further Confounders in Trial Results.
Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors. 22(4) [DOI] 10.1080/10903127.2017.1408729. [PMID] 29338483.
2017
Machine learning algorithm for automatic detection of CT-identifiable hyperdense lesions associated with traumatic brain injury
.
2017
Prehospital Intubation is Associated with Favorable Outcomes and Lower Mortality in ProTECT III.
Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors. 21(5):539-544 [DOI] 10.1080/10903127.2017.1315201. [PMID] 28489506.
2017
Society for Academic Emergency Medicine Statement on Plagiarism.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 24(10):1290-1292 [DOI] 10.1111/acem.13241. [PMID] 28628260.
2017
The Advanced Reperfusion Era: Implications for Emergency Systems of Ischemic Stroke Care.
Annals of emergency medicine. 69(2):192-201 [DOI] 10.1016/j.annemergmed.2016.06.042. [PMID] 27600649.
2016
Simulation-based Randomized Comparative Assessment of Out-of-Hospital Cardiac Arrest Resuscitation Bundle Completion by Emergency Medical Service Teams Using Standard Life Support or an Experimental Automation-assisted Approach.
Simulation in healthcare : journal of the Society for Simulation in Healthcare. 11(6):365-375 [PMID] 27509064.
View on: PubMed
2015
Advancing Patient-centered Outcomes in Emergency Diagnostic Imaging: A Research Agenda.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 22(12):1435-46 [DOI] 10.1111/acem.12832. [PMID] 26574729.
2015
American College of Surgeons Trauma Quality Improvement Program Guidelines, Traumatic Brain Injury
Journal of the American College of Surgeons.
2015
Optimizing Patient-centered Communication and Multidisciplinary Care Coordination in Emergency Diagnostic Imaging: A Research Agenda.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 22(12):1427-34 [DOI] 10.1111/acem.12826. [PMID] 26575785.
2015
The Emergency Medicine Debate on tPA for Stroke: What Is Best for Our Patients? Efficacy in the First Three Hours.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 22(7):852-5 [DOI] 10.1111/acem.12712. [PMID] 26113369.
2015
Written Informed Consent for Computed Tomography of the Abdomen/Pelvis is Associated with Decreased CT Utilization in Low-Risk Emergency Department Patients.
The western journal of emergency medicine. 16(7):1014-24 [DOI] 10.5811/westjem.2015.9.27612. [PMID] 26759646.
2014
Gender differences in neurological emergencies part II: a consensus summary and research agenda on traumatic brain injury.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 21(12):1414-20 [DOI] 10.1111/acem.12532. [PMID] 25420582.
2014
Very early administration of progesterone for acute traumatic brain injury.
The New England journal of medicine. 371(26):2457-66 [DOI] 10.1056/NEJMoa1404304. [PMID] 25493974.
2011
Informed consent for computed tomography.
The American journal of emergency medicine. 29(2):230-2 [DOI] 10.1016/j.ajem.2010.09.006. [PMID] 21115314.
2007
Intracranial hemorrhage in asymptomatic neonates: prevalence on MR images and relationship to obstetric and neonatal risk factors.
Radiology. 242(2):535-41 [PMID] 17179400.
View on: PubMed
2006
The Chiari pseudotumor cerebri syndrome: symptom recurrence after decompressive surgery for Chiari malformation type I.
Pediatric neurosurgery. 42(1):14-9 [PMID] 16357496.
View on: PubMed
2005
Adult tethered cord syndrome in patients with postrepair myelomeningocele: an evidence-based outcome study.
Journal of neurosurgery. 102(2 Suppl):150-6 [PMID] 16156223.
View on: PubMed

Grants

Apr 2021 ACTIVE
A multicenter, adaptive, prospective, randomized trial evaluating the efficacy and safety of antithrombotic strategies in patients with COVID-19 following hospital discharge
Role: Principal Investigator
Funding: COVANCE INC via NATL INST OF HLTH NHLBI
Jul 2020 ACTIVE
ACTIV-4 Infected Outpatient Study
Role: Project Manager
Funding: UNIV OF PITTSBURGH via NATL INST OF HLTH NHLBI
Jun 2020 – May 2021
Clinical Trial of COVID-19 Convalescent Plasma in Outpatients (C3PO)
Role: Principal Investigator
Funding: UNIV OF MICHIGAN ANN ARBOR via NATL INST OF HLTH NHLBI
Sep 2019 ACTIVE
Biomarkers in the Brain Oxygen Optimization in Severe TBI Trial (Bio-BOOST)
Role: Principal Investigator
Funding: UNIV OF MICHIGAN ANN ARBOR via US ARMY MED RES ACQUISITION
Sep 2019 ACTIVE
Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (ICECAP) Trial
Role: Principal Investigator
Funding: UNIV OF MICHIGAN ANN ARBOR via NATL INST OF HLTH NHLBI
Jul 2019 ACTIVE
Brain Oxygen Optimization in Severe Traumatic Brain Injury – Phase 3 (BOOST-3)
Role: Principal Investigator
Funding: UNIV OF MICHIGAN ANN ARBOR via NATL INST OF HLTH NINDS
Jul 2019 – Jul 2021
FY20 VA IPA for Kobaissy
Role: Project Manager
Funding: US DEPT OF VET AFF GAINESVILLE MED CTR
Jul 2019 – Jun 2020
Johns Hopkins-Tufts Trial Innovation Center
Role: Co-Investigator
Funding: JOHNS HOPKINS UNIVERSITY via NATL INST OF HLTH NCATS
Jun 2019 – May 2021
SIREN Hub Year 3
Role: Principal Investigator
Funding: EMORY UNIV via NATL INST OF HLTH NINDS
Jul 2018 ACTIVE
Brain Oxygen Optimization in Severe TBI Phase-3 (BOOST-3) Trial CSPR #002
Role: Principal Investigator
Funding: UNIV OF MICHIGAN ANN ARBOR via NATL INST OF HLTH NINDS
Apr 2017 – Jun 2021
OoR CTSI Institutional Matching Support
Role: Project Manager
Funding: UF DIV OF SPONSORED RES MATCHING FUNDS

Contact Details

Phones:
Business:
(352) 265-5911
Administrative Assistant:
Debra J Beck
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